|
An Li,
PhD., Samuel & Catherine Epstein Professor Environmental
and Occupational Health Sciences School of Public Health, University of Illinois at Chicago Phone
(312) 996-9597, Fax (312) 413-9898, Email: anli@uic.edu Faculty Profile, PubMed,
Google
Scholar, Research
Gate, Publons, ORCID Ph.D. in
Water Chemistry. 1993. University
of Wisconsin - Madison
MS in
Environmental Engineering. 1988. Utah State
University |
The prohibition of new carcinogenic products,
reduction of toxins in use, and right-to-know laws - these are among the
legislative proposals which could reverse the cancer epidemic. - Dr. Samuel
Epstein (1926 – 2018)
Research
As an
environmental chemist, I study and research on how human activities influence
the natural environment and how the changes in turn affect human health. Among countless
number of chemicals, my research team particularly focuses on persistent, bioaccumulative, and potentially toxic organic chemicals.
We have measured many groups of legacy and emerging pollutants in air, water,
soil, dust, sludge, and sediment. The data allowed us to see how these
chemicals transport and transform in the ecosystem, and how such behavior
depends on molecular structure and other factors. We also investigate the
presence of such pollutants in human. For example, our data from blood and
placenta tissue samples are being used in epigenetic studies and are useful to
understand the mechanisms of across-placenta transfer among chemicals.
Our
laboratory consists of 8 well equipped rooms with a total area of >3,500 sqft. The major gas chromatography (GC) and mass
spectrometry (MS) instruments include Agilent 7890/7000 GC-MS/MS, two
6890+/5973 GC-MS (EI/NCI/PCI), and 6890+ with ECD. We also have an Agilent
1200/6410 HPLC/MSMS, and two Waters Micromass Quattro
Micro LC/MSMS systems. Other major equipment includes Dionex
ASE350 accelerated solvent extraction system, Labconco
4.5L and Virtis model 2K freeze drying systems,
Beckman Avanti30 centrifuge, etc., as well as various air and sediment sampling
equipment.
The major projects are listed
below:
- Method Development for Analyzing Microplastics in Sediment of Lake
Michigan
- Great
Lakes Sediment Surveillance Program (GLSSP) (Featured in
cover story on C&EN and online,
and in UIC
News. See sampling video on YouTube.)
- NCS
Formative Research - Organic Contaminants in Placenta Tissue (The National Childrenճ Study)
- Debromination
of PBDEs in Aquatic Sediments (NSF
Summary)
- Method
Development for the Analysis of PBDEs in Human Placenta Tissue (NIEHS Summary)
- Historical
and Emerging Halogenated Flame Retardants in Sediment of the Great Lakes (EPA Final Report)
- Measuring
Water Ingestion Among Water Recreators (WERF Final Report)
- Chronology
of PBDE Air Deposition in the Great Lakes from Sedimentary Records (EPA Final Report)
- Source
Apportionment of Indoor PAHs in Urban Residence Homes (EPA
website, NUATRC
Final Report)
-
EOHS543/CME523: Environmental Organic Chemistry
-
EOHS440/CME411: Chemistry for Environmental Professionals
- EOHS594:
Water and Health Seminar
Books
Erik R. Christensen and An Li. Physical
and Chemical Processes in the Aquatic Systems. John Wiley & Sons, Inc.
2014. ISBN: 978-1-118-11176-5.
An Li, Shinsuke Tanabe, Guibin
Jiang, John P. Giesy, Paul K. S. Lam (Eds). Persistent
Organic Pollutants in Asia - Sources, Distributions, Transport, and Fate.
Elsevier Publications. 2007. ISBN-13: 978-0-08-045132-9. ISBN-10:
0-08-045132-2. [pdf
access through institution subscription]
Recent
Journal Publications [List of
Publications]
Yingxue Liu, An Li, Qi An, Kai Liu, Ping
Zheng, Shanshan Yin, Weiping Liu. Prenatal and
postnatal transfer of perfluoroalkyl substances from mothers to their
offspring. Critical Reviews in Environmental Science and Technology. 51,
1886556. 2021.
Yingxue Liu, An Li, Susan
Buchanan, Weiping Liu. Review article: Perfluoroalkyl
substances in mothers and infants: prenatal and postnatal exposure and transfer
of congeners, isomers, and enantiomers. Environment
International. 144, 106012. 2020.
Ruijie Zhang, Kefu
Yu, An Li, Weibin Zeng, Tian Lin, Yinghui Wang. Occurrence, phase distribution, and
bioaccumulation of organophosphate esters (OPEs) in mariculture farms of the Beibu Gulf, China: A health risk assessment through seafood
consumption. Environmental Pollution.
263, Part B, 114426. 2020.
Jiehong Guo, Zhuona
Li, Prabha Ranasinghe, Karl J. Rockne, Neil C. Sturchio,
John P Giesy, An Li. Halogenated flame
retardants in sediments from the Upper Laurentian Great Lakes: Implications to
long-range transport and evidence of long-term transformation. Journal of Hazardous Materials. 384,
121346. 2020.
Xu Han, Lingling
Meng, Yuedong Xu, Feng Zhangd,
Yingming Li, An Li, Mary E. Turyk, Ruiqiang Yang, Pu Wang, Jianqing Zhang, Qinghua Zhang, Guibin Jiang. Exposure to organochlorine pesticides and the
risk of type 2 diabetes in the population of East China. Ecotoxicology and Environmental Safety, 190, 110125, 2020.
Ruijie Zhang, Kefu
Yu, Yinghui Wang, An Li, Changgui
Pan, Minwei Han, Yang Ding, Weibin
Zeng, Ruiling Zhang, Xueyong
Huang. Antibiotics in coral reef fishes from the South China Sea: Occurrence,
distribution, bioaccumulation, and dietary exposure risk to human. Science of the Total Environment. 704, 135288. 2020.
Xu Han, Lingling
Meng, Yingming Li, An Li, Mary E. Turyk, Ruiqiang Yang, Pu Wang, Ke Xiao, Junpeng Zhao, Jianqing Zhang, Qinghua Zhang, Guibin Jiang. Associations between the exposure to persistent
organic pollutants and type 2 diabetes in East China: a case-control study. Chemosphere, 241, 125030. 2020.
Minwei Han, Ruijie
Zhang, Kefu Yu, An Li, Yinghui
Wang, Xueyong Huang. Polycyclic aromatic hydrocarbons
(PAHs) in Corals of the South China Sea: Occurrence, Distribution,
Bioaccumulation, and Considerable Role of Coral Mucus. Journal of Hazardous Materials, 384, 121299. 2020.
Erik R. Christensen, Ruijie
Zhang, Garry Codling, John P. Giesye, An Li.
Poly- and per-fluoroalkyl compounds in sediments of the Great Lakes: Loadings,
temporal trends, and sources determined by positive matrix factorization. Environmental Pollution. 255, 113166.
2019.
Xu Han, Lingling
Meng, Yingming Li, An Li, Mary Turyk, Ruiqiang Yang, Pu Wang, Ke Xiao, Wenjuan Li, Junpeng Zhao, Qinghua Zhang, Guibin Jiang. Associations between exposure to persistent
organic pollutants and thyroid function in a case-control study of East China. Environmental Science and Technology,
53, 9866-9875. 2019.
Tian Lin, Zilan Wu,
An Li, Shanshan Zhou, Huan He, Jiehong Guo, Limin Hu, Yuanyuan Li, Zhigang
Guo. Sedimentary records of polychlorinated biphenyls in the East China
Marginal Seas and Great Lakes: Significance of recent rise of emissions in
China and environmental implications. Environmental
Pollution. 254, Part A, 112972. 2019.
Xiaoxue Pan, Chenguang
Li, Jing Chena, Jiaoqin Liu, Jiali
Ge, Jiayi Yao, Siyuan Wang,
Zunyao Wang, Ruijuan Qu, An
Li. The photodegradation of 1,3,6,8-tetrabromocarbazole in n-hexane and in
solid-mediated aqueous system: Kinetics and transformation mechanisms. Chemical Engineering Journal, 375,
121986. 2019.
Ruijie Zhang, Kefu
Yu, An Li, Yinghui Wang, Ruiling
Zhang, Minwei Han, Weibin
Zeng, Xueyong Huang, Zhenjun
Qin, Jiying Pei. Antibiotics in corals of the South China
Sea: occurrence, distribution, bioaccumulation, and considerable role of coral
mucus. Environmental Pollution, 250,
503-510. 2019.
Shanshan Zhou, Xiaoxue
Pan, Qiangzhi Tang, Hongbin Zhu, Lu Zhao, Jiehong Guo, Zunyao Wang, Weiping Liu, An Li. Photochemical Degradation of
Polyhalogenated Carbazoles in Hexane by Sunlight. Science of The Total Environment, 671, 622-631. 2019.
Book
Chapters
An Li. Predicting Cosolvency for Pharmaceutical
and Environmental Applications. In: Handbook of Solvents, Volume 2: Use, Health,
and Environment. Wypych, G. Ed. ChemTec
Publishing, Toronto, Canada. Chapter 13.21.2. pp. 186-210. 2014. ISBN
978-1-895198-65-2
Hua Wei and An Li. Semi-volatile
Organic Pollutants in the Gaseous and Particulate Phases in Urban Air. In: Urban Airborne Particulate Matter: Origins,
Chemistry, Fate and Health Impacts. Fathi Zereini & Clare Wiseman (Eds). Springer Publishing
Company. 2010. pp. 339-362. ISBN: 978-3-642-12277-4
Qinghua Zhang, Yawei
Wang, An Li, Guibin Jiang. Polychlorinated Dibenzo-p-dioxins,
Dibenzofurans, and Biphenyls, and Polybrominated Diphenyl Ethers in China. In: Persistent Organic Pollutants in Asia -
Sources, Distributions, Transport, and Fate. An Li, Shinsuke
Tanabe, Guibin Jiang, John P. Giesy,
Paul K. S. Lam (Eds). Elsevier Publications. 2007. ISBN-10: 0-08-045132-2.
Chapter 4.
An Li. Predicting Cosolvency for
Pharmaceutical and Environmental Applications. In: Handbook of Solvents. Wypych,
G. Ed. ChemTec Publishing, Toronto, Canada. Chapter 14.21.2.
pp. 997-1016. 2001. ISBN 1-895198-24-0.
Research
Team
Yi-Ling Cheng – MS student, 2018-2020
Ruijie Zhang – Visiting Scholar, 2018-2020
Cornelia Forrester – MS student, 2017-present
Xiaoxue Pan – Visiting PhD student,
2017-2018.
Qiaozhi Tang – Visiting PhD student,
2016-2017.
Tian Lin – Visiting Scholar, 2015-2018.
Huan He - Visiting Scholar, 2015-2016.
Shanshan Zhou - Visiting Scholar, 2015-2016.
Jiehong Guo - Ph.D. 2015. Spatial
Distribution and Time Trend of Organic Pollutant Chemicals in the Sediments of
Upper Great Lakes.
Denisse Herrera - Undergraduate Research
Assistant. 2014-2016.
Ishan Parikh - Undergraduate Research
Assistant. 2013-2016.
Zhuona Li - Postdoc Research Associate.
2013-2014.
Priyanthi Shyamalee
Dassanayake - PhD 2014. Legacy and Emerging Environmental Organic Pollutants
in Human Placenta and Blood.
Prabha Ranasinghe - MS 2014. Spatial Distribution of
Persistent Organic Pollutants in Surface Sediment of Lake Huron.
Ying Wang - Visiting Scholar 2013-2014.
Admasu Wondmagegn - Undergraduate Research
Assistant. 2012-present.
Yawei Wang - Visiting Scholar 2012-2014.
Xiaowen Lu - Visiting Scholar 2012.
Yulin Xia - MS 2012. Polybrominated
Diphenyl Ethers in Human Placentas in the United States
Jessica Nanes - MS 2012. Legacy Persistent
Organic Pollutants in Human Placental Tissue from the United States
Andy Sandy - Postdoc Associate. 2010-2012.
Hua Wei - PhD 2012. Polybrominated Diphenyl Ethers
in Sediments from Arkansas, Illinois and Indiana of the United States.
Suraj Panthi- MS 2010. Quantification of
Cyanuric Acid in Outdoor Swimming Pool Water and Human Urine Samples Using
HPLC.
Colin McLeod - Student research assistant.
2009-2010.
Amit Patel - UIC Honor College. Undergraduate research
assistant. 2009-2010.
Ruiqiang Yang - Visiting Scholar. 2009-2010.
Yue Huang - Postdoc Associate 2009.
Priyanthi Shyamalee
Dassanayake - MS 2008. Preliminary method development to analyze
polybrominated diphenyl ethers in human placenta.
Hua Wei -MS 2007. Analytical Method Enhancement for
Polybrominated Diphenyl Ethers in Environmental Samples.
Rachel C. Chen -2006. High School Research
Intern. Intel Science Talent Search Semi-finalist.
Wenlu Song - PhD 2005. Polybrominated
Diphenyl Ethers in the Sediment of the Great Lakes.
Justin C. Ford - MS 2005. Sedimentation in the
Laurentian Great Lakes as Determined by Alpha Spectroscopy.
Lymari Ruiz-Sanchez - MS 2003. Analytical Method
Development for Mycotoxins in House Dust Samples.
Gwennetta M. Butler - MS 2003. Solubility of
4-chlorobiphenyl in Water-Alcohol Mixtures at Four Temperatures.
Todd M. Schoonover - MS 2002. Polycyclic Aromatic Hydrocarbons
in Residential Air of Ten Chicago Area Homes.
Jim Q. Zou - PhD student research assistant. 2000-2002.
Xiaoyu Liu
- MS student
research assistant. 1998-2000.
Jae-Kil Jang - PhD 2001. Spatial and Temporal
Distribution and Source Identification of Priority Pollutants in Lake Calumet
Area.
Felice Norlock - MS 2000. Method Development on
the Analysis of Polycyclic Aromatic Hydrocarbons in Urban Residence Homes.
Kent A.
Cheung - MS 1998.
Cosolvent Enhanced Electrokinetic Remediation of Soil Contaminated with
Polycyclic Aromatic Hydrocarbons