An Li, PhD., Samuel & Catherine Epstein Professor

Environmental and Occupational Health Sciences  

School of Public Health, University of Illinois at Chicago

Phone (312) 996-9597, Fax (312) 413-9898, Email: anli@uic.edu

 

Faculty Profile, Google Scholar, Research Gate, ResearcherID, ORCID,

 

Ph.D. in Water Chemistry. 1993. University of Wisconsin - Madison

MS in Environmental Engineering. 1988. Utah State University

 

 

 

The prohibition of new carcinogenic products, reduction of toxins in use, and right-to-know laws - these are among the legislative proposals which could reverse the cancer epidemic. - Dr. Samuel Epstein (1926 – 2018)

 

Research

As an environmental chemist, I study and research on how human activities influence the natural environment and how the changes in turn affect human health. Among countless number of chemicals, my research team particularly focuses on persistent, bioaccumulative, and potentially toxic organic chemicals. We have measured many groups of legacy and emerging pollutants in air, water, soil, dust, sludge, and sediment. The data allowed us to see how these chemicals transport and transform in the ecosystem, and how such behavior depends on molecular structure and other factors. We also investigate the presence of such pollutants in human. For example, our data from blood and placenta tissue samples are being used in epigenetic studies and are useful to understand the mechanisms of across-placenta transfer among chemicals.

Our laboratory consists of 8 well equipped rooms with a total area of >3,500 sqft. The major gas chromatography (GC) and mass spectrometry (MS) instruments include Agilent 7890/7000 GC-MS/MS, two 6890+/5973 GC-MS (EI/NCI/PCI), and 6890+ with ECD. We also have an Agilent 1200/6410 HPLC/MSMS, and two Waters Micromass Quattro Micro LC/MSMS systems. Other major equipment includes Dionex ASE350 accelerated solvent extraction system, Labconco 4.5L and Virtis model 2K freeze drying systems, Beckman Avanti30 centrifuge, etc., as well as various air and sediment sampling equipment.

The major projects are listed below:

- Method Development for Analyzing Microplastics in Sediment of Lake Michigan

- Great Lakes Sediment Surveillance Program (GLSSP) (Featured in cover story on C&EN and online, and in UIC News. See sampling video on YouTube)

- NCS Formative Research - Organic Contaminants in Placenta Tissue (The National ChildrenŐs Study Archive)

- Debromination of PBDEs in Aquatic Sediments (NSF Summary)

- Method Development for the Analysis of PBDEs in Human Placenta Tissue (NIEHS Summary)

- Historical and Emerging Halogenated Flame Retardants in Sediment of the Great Lakes (EPA Final Report)

- Measuring Water Ingestion Among Water Recreators (WERF Final Report)

- Chronology of PBDE Air Deposition in the Great Lakes from Sedimentary Records (EPA Final Report)

- Source Apportionment of Indoor PAHs in Urban Residence Homes (EPA website, NUATRC Final Report)

 

Teaching

- EOHS543/CME523: Environmental Organic Chemistry

- EOHS440/CME411: Chemistry for Environmental Professionals

- EOHS594: Water and Health Seminar

 

Books

Erik R. Christensen and An Li. Physical and Chemical Processes in the Aquatic Systems. John Wiley & Sons, Inc. 2014. ISBN: 978-1-118-11176-5.

An Li, Shinsuke Tanabe, Guibin Jiang, John P. Giesy, Paul K. S. Lam (Eds). Persistent Organic Pollutants in Asia - Sources, Distributions, Transport, and Fate. Elsevier Publications. 2007. ISBN-13: 978-0-08-045132-9. ISBN-10: 0-08-045132-2. [pdf access through institution subscription]

 

Recent Journal Publications [List of Publications]

Shanshan Zhou, Xiaoxue Pan, Qiangzhi Tang, Hongbin Zhu, Lu Zhao, Jiehong Guo, Zunyao Wang, Weiping Liu, An Li. Photochemical Degradation of Polyhalogenated Carbazoles in Hexane by Sunlight. (in review) 2018.

Zilan Wu, Tian Lin, An Li, Shanshan Zhou, Huan He, Jiehong Guo, Limin Hu, Yuanyuan Li, Zhigang Guo. Sedimentary records of polychlorinated biphenyls in the East China Marginal Seas: Significance of recent rise of unintentional emissions in China and global environmental implications. (in revision). 2018.

Soheil Hosseini, Solidea M.C. Bonina, Margaret B. Corcoran, Colin Smalley, Jiehong Guo, Neil C. Sturchio, An Li, and Karl J. Rockne*. Spatial and temporal trends in black carbon deposition to the upper Great Lakes in the last 100 Years. (in revision) 2018.

Solidea M.C. Bonina, Garry Codling, Margaret B. Corcoran, Jiehong Guo, John P. Giesy, An Li, Neil C. Sturchio, Karl J. Rockne. Temporal and spatial differences in deposition of organic matter and black carbon in Lake Michigan sediments over the period 1850–2010. Journal of Great Lakes Research. 44(4): 705-715. 2018.

Margaret B. Corcoran, Mahmoud Sherif, Colin Smalley, An Li, Karl J. Rockne, John P. Giesy, Neil C. Sturchio. Accumulation rates, focusing factors, and chronologies from depth profiles of 210Pb and 137Cs in sediments of the Laurentian Great Lakes. Journal of Great Lakes Research. 44(4): 693-704. 2018.

An Li, Jiehong Guo, Zhuona Li, Tian Lin, Shanshan Zhou, Huan He, Prabha G. Ranasinghe, Neil C. Sturchio, Karl J. Rockne, John P. Giesy. Legacy Polychlorinated Organic Pollutants in the Sediment of the Great Lakes. Journal of Great Lakes Research. 44(4): 682-692. 2018.

Garry Codling, Karl. J. Rockne, An Li, Neil C. Sturchio, Mahmoud Sherif, Kyunghee Ji, Hui Peng, Timothy J. Tse, and John P. Giesy. Spatial and temporal trends in poly- and per-fluorinated compounds in the Laurentian Great Lakes Erie, Ontario and St. Clair. Environmental Pollution, 237, 396-405. 2018.

Garry Codling, Soheil Hosseini, Margaret B. Corcoran, Solidea Bonina, Tian Lin, An Li, Neil C. Sturchio, Karl. J. Rockne, Kyunghee Ji, Hui Peng, and John P. Giesy. Current and historical concentrations of poly and perfluorinated compounds in sediments of the northern Great Lakes - Superior, Huron, and Michigan. Environmental Pollution, 236:373-381. 2018.

Jiehong Guo, Kevin Romanak, Stephen Westenbroek, An Li, Russell Kreis, Ronald A. Hites, and Marta Venier. Updated Polychlorinated Biphenyl Mass Budget for Lake Michigan. Environmental Science and Technology, 51 (21), 12455–12465. 2017.

Shanshan Zhou, Jie Fua, Jianjie Fu, Qiaozhi Tang, Minfeng Dong, Yongqiang Pan, An Li, Weiping Liu, Huan He. Distribution and source characterization of Dechlorane Plus and structurally-related compounds in sediment from Taizhou, an intense e-waste recycling area in eastern China: Comparison with polybrominated diphenyl ethers. Chemosphere, 184, 1202-1208. 2017.

Dandan Cao, Jiehong Guo, Yawei Wang, Zhuona Li, Kang Liang, Margaret B. Corcoran, Soheil Hosseini, Solidea M. C. Bonina, Karl J. Rockne, Neil C. Sturchio, John P. Giesy, Jingfu Liu, An Li, and Guibin Jiang. Organophosphate Esters in Sediment of the Great Lakes. Environmental Science and Technology, 51(3), 1441–1449. 2017.  Great Lakes Echo

Meiqing Jin, Jie Fu, Bin Xue, Shanshan Zhou, Lina Zhang, An Li. Distribution and enantiomeric profilesof organochlorine pesticides in surface sediments from the Bering Sea, Chukchi Sea and adjacent Arctic areas. Environmental Pollution, 222, 109-117, 2017.

Jiehong Guo, Zhuona Li, Prabha G. Ranasinghe, Solidea M.C. Bonina, Soheil Hosseini, Margaret Corcoran, Colin Smalley, Karl J. Rockne, Neil C. Sturchio, John P. Giesy, An Li. Spatial and Temporal Trends of Polyhalogenated Carbazoles in Sediments of Upper Great Lakes — Insights into their Origin. Environmental Science and Technology, 51, 89-97. http://dx.doi.org/10.1021/acs.est.6b06128 (open access). Also see UIC News Release. 2017.

Hui Peng, Chunli Chen, Jenna Cantin, David M.V. Saunders, Jianxian Sun, Song Tang, Garry Codling, Markus Hecker, Steve Wiseman, Paul D. Jones, An Li, Karl J. Rockne, Neil C. Sturchio, Minghong Cai, John. P. Giesy. Untargeted Screening and Distribution of Organo-iodine Compounds in Sediments from Lake Michigan and the Arctic Ocean. Environmental Science and Technology, 50, 10097−10105. 2016.

Mingliang Fang, Jiehong Guo, Da Chen, An Li, Andrey Massarsky, David E. Hinton, Wu Dong. Halogenated Carbazoles Induce Cardiotoxicity in Developing Zebrafish Embryos (Danio Rerio). Environmental Toxicology and Chemistry. 35(10), 2523–2529. 2016. [Among the ET&C top 10 exceptional papers of 2016]

Jiehong Guo, Zhuona Li, Prabha Ranasinghe, Solidea Bonina, Soheil Hosseini, Margaret B. Corcoran, Colin Smalley, Rajashankar Kaliappan, Yan Wu, Da Chen, Andy L. Sandy, Yawei Wang, Karl J. Rockne, Neil C. Sturchio, John P. Giesy, An Li. Atrazine and Related Compounds in Sediments of Upper Great Lakes. Environmental Science and Technology, 50, 7335−7343. 2016.

Ruiqiang Yang, Ting Xie, An Li, Handong Yang, Simon Turner, Guangjian Wu, Chuanyong Jing.  Sedimentary records of polycyclic aromatic hydrocarbons (PAHs) in remote lakes across the Tibetan Plateau. Environmental Pollution. 214, 1–7. 2016.

Maya A. Kappil, Qian Li, An Li, Priyanthi S. Dassanayake, Yulin Xia, Jessica A. Nanes, Philip J. Landrigan, Christopher J. Stodgell, Kjersti M. Aagaard, Eric E. Schadt, Nancy Dole, Michael Varner, John Moye, Carol Kasten, Richard K. Miller, Yula Ma, Jia Chen, Luca Lambertini. In utero exposures to environmental organic pollutants disrupt epigenetic marks linked to fetoplacental development. Environmental Epigenetics 2(1), 1–7. 2016.

Yan Wu, Jeremy Moore, Jiehong Guo, An Li, Keith Grasman, Da Chen. Multi-Residue Determination of a Suite of Polyhalogenated carbazoles in Aquatic Sediments. Journal of Chromatography A, 1434, 111-118, 2016.

Yonghong Zou, Azivy Che Aziz, Hua Wei, Erik R. Christensen, Karl Rockne, An Li. PBDEs and Debromination in Arkansas Water Bodies Analyzed by Positive Matrix Factorization. Environmental Science and Technology, 50 (3), 1359–1367. 2016.

An Li, Jie Gao, Sally Freels, Jun Huang, Gang Yu. Predicting GC Relative Retention Times for Polychlorinated Biphenyls Using Chlorine Substitution Pattern Contribution Method. Journal of Chromatography A, 1427, 161–169. 2016.

Hui Peng, Chunli Chen, Jenna Cantin, David M.V. Saunders, Jianxian Sun, Song Tang, Garry Codling, Markus Hecker, Steve Wisema, Paul D. Jones, An Li, Karl J. Rockne, Neil C. Sturchio, John. P. Giesy. Untargeted Screening and Distribution of Organo-Bromine Compounds in Sediments of Lake Michigan. Environmental Science and Technology. 50 (1): 321–330. 2016.

 

Book Chapters

An Li. Predicting Cosolvency for Pharmaceutical and Environmental Applications. In: Handbook of Solvents, Volume 2: Use, Health, and Environment. Wypych, G. Ed. ChemTec Publishing, Toronto, Canada. Chapter 13.21.2. pp. 186-210. 2014. ISBN 978-1-895198-65-2

Hua Wei and An Li. Semi-volatile Organic Pollutants in the Gaseous and Particulate Phases in Urban Air. In: Urban Airborne Particulate Matter: Origins, Chemistry, Fate and Health Impacts. Fathi Zereini & Clare Wiseman (Eds). Springer Publishing Company. 2010. pp. 339-362. ISBN: 978-3-642-12277-4

Qinghua Zhang, Yawei Wang, An Li, Guibin Jiang. Polychlorinated Dibenzo-p-dioxins, Dibenzofurans, and Biphenyls, and Polybrominated Diphenyl Ethers in China. In: Persistent Organic Pollutants in Asia - Sources, Distributions, Transport, and Fate. An Li, Shinsuke Tanabe, Guibin Jiang, John P. Giesy, Paul K. S. Lam (Eds). Elsevier Publications. 2007. ISBN-10: 0-08-045132-2. Chapter 4.

An Li. Predicting Cosolvency for Pharmaceutical and Environmental Applications. In: Handbook of Solvents. Wypych, G. Ed. ChemTec Publishing, Toronto, Canada. Chapter 14.21.2. pp. 997-1016. 2001. ISBN 1-895198-24-0.

 

Research Team

Yi-Ling Cheng – MS student, 2018-present

Ruijie Zhang – Visiting Scholar, 2018-present

Cornelia Forrester – MS student, 2017-present

Xiaoxue Pan – Visiting PhD student, 2017-2018.

Qiaozhi Tang – Visiting PhD student, 2016-2017.

Tian Lin – Visiting Scholar, 2015-2018.

Huan He - Visiting Scholar, 2015-2016.

Shanshan Zhou - Visiting Scholar, 2015-2016.

Jiehong Guo - Ph.D. 2015. Spatial Distribution and Time Trend of Organic Pollutant Chemicals in the Sediments of Upper Great Lakes.

Denisse Herrera - Undergraduate Research Assistant. 2014-2016.

Ishan Parikh - Undergraduate Research Assistant. 2013-2016.

Zhuona Li - Postdoc Research Associate. 2013-2014.

Priyanthi Shyamalee Dassanayake - PhD 2014. Legacy and Emerging Environmental Organic Pollutants in Human Placenta and Blood.

Prabha Ranasinghe - MS 2014. Spatial Distribution of Persistent Organic Pollutants in Surface Sediment of Lake Huron.

Ying Wang - Visiting Scholar 2013-2014.

Admasu Wondmagegn - Undergraduate Research Assistant. 2012-present.

Yawei Wang - Visiting Scholar 2012-2014.

Xiaowen Lu - Visiting Scholar 2012.

Yulin Xia - MS 2012. Polybrominated Diphenyl Ethers in Human Placentas in the United States

Jessica Nanes - MS 2012. Legacy Persistent Organic Pollutants in Human Placental Tissue from the United States

Andy Sandy - Postdoc Associate. 2010-2012.

Hua Wei - PhD 2012. Polybrominated Diphenyl Ethers in Sediments from Arkansas, Illinois and Indiana of the United States.

Suraj Panthi- MS 2010. Quantification of Cyanuric Acid in Outdoor Swimming Pool Water and Human Urine Samples Using HPLC.

Colin McLeod - Student research assistant. 2009-2010.

Amit Patel - UIC Honor College. Undergraduate research assistant. 2009-2010.

Ruiqiang Yang - Visiting Scholar. 2009-2010.

Yue Huang - Postdoc Associate 2009.

Priyanthi Shyamalee Dassanayake - MS 2008. Preliminary method development to analyze polybrominated diphenyl ethers in human placenta.

Hua Wei -MS 2007. Analytical Method Enhancement for Polybrominated Diphenyl Ethers in Environmental Samples.

Rachel C. Chen -2006. High School Research Intern. Intel Science Talent Search Semi-finalist.

Wenlu Song - PhD 2005. Polybrominated Diphenyl Ethers in the Sediment of the Great Lakes.

Justin C. Ford - MS 2005. Sedimentation in the Laurentian Great Lakes as Determined by Alpha Spectroscopy.

Lymari Ruiz-Sanchez - MS 2003. Analytical Method Development for Mycotoxins in House Dust Samples.

Gwennetta M. Butler - MS 2003. Solubility of 4-chlorobiphenyl in Water-Alcohol Mixtures at Four Temperatures.

Todd M. Schoonover - MS 2002. Polycyclic Aromatic Hydrocarbons in Residential Air of Ten Chicago Area Homes.

Jim Q. Zou - PhD student research assistant. 2000-2002.

Xiaoyu Liu - MS student research assistant. 1998-2000.

Jae-Kil Jang - PhD 2001. Spatial and Temporal Distribution and Source Identification of Priority Pollutants in Lake Calumet Area.

Felice Norlock - MS 2000. Method Development on the Analysis of Polycyclic Aromatic Hydrocarbons in Urban Residence Homes.

Kent A. Cheung - MS 1998. Cosolvent Enhanced Electrokinetic Remediation of Soil Contaminated with Polycyclic Aromatic Hydrocarbons